Searchable abstracts of presentations at key conferences in endocrinology

ea0090oc11.3 | Oral Communications 11: Late Breaking | ECE2023

Effects of semaglutide, PYY3-36, antagonists of the GLP-1/NPY-Y2 receptors, and empagliflozin on non-alcoholic fatty liver disease

Haerting Niklas , Herzog Gloria , Nickel Alexander , Kohlhaas Michael , Fassnacht Martin , Ziegler Christian , Dischinger Ulrich

Background: Non-alcoholic fatty liver disease (NAFLD) is a common comorbidity in obese individuals. GLP-1 agonists, such as semaglutide, and SGLT-2 inhibitors, such as empagliflozin, are well known to be beneficial in NAFLD, while other incretins, like peptide tyrosine tyrosine 3-36 (PYY3-36), might be also useful for the treatment of NAFLD. We directly compared the effects of semaglutide alone and in combination with peptide tyrosine tyrosine 3-36 (PYY3-36), empagliflozin and...